Suspected malignant hyperthermia during sevoflurane anesthesia.

نویسندگان

  • Shu-Chia Hsu
  • Wei-Tai Huang
  • Huei-Ming Yeh
  • Allen Yi-Jer Hsieh
چکیده

Malignant hyperthermia is a rare anesthetic-related disorder. We present a case with unusual presentation. A boy aged 3 years and 9 months who was scheduled for Hotz's operation presented normally before the operation. Anesthesia was induced by atropine, thiopental and sevoflurane. Trachea intubation was facilitated by succinylcholine. Jaw stiffness was first noted although trachea was intubated without difficulty. The following tachycardia, hypercapnia and hyperthermia led to the diagnosis of malignant hyperthermia. Symptoms were relieved dramatically after the discontinuation of sevoflurane. Molecular genetic testing identified a novel ryanodine receptor (RYR1) mutation in exon 39, which confirmed malignant hyperthermia susceptibility in this patient.

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عنوان ژورنال:
  • Journal of the Chinese Medical Association : JCMA

دوره 70 11  شماره 

صفحات  -

تاریخ انتشار 2007